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To identify THC-specific datasets, we queried GEO using the keywords THC and Delta-9-tetrahydrocannabinol, while CBD-specific datasets were retrieved using CBD and Cannabidiol. Studies were included if they met the following criteria: 1) the model organism was human, mouse, rat, or rhesus macaque to focus on mammalian species with higher translational potential

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As awareness of tobacco-related health concerns grew, many smokers moved toward lighter alternatives, hoping to reduce their nicotine intake without quitting entirely

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